9 smoothies high in calories, perfect for cancer patients. photo of 2 brown smoothies with banana slices next to the glasses

9 Easy Smoothies High in Calories [Perfect for Cancer Patients]

It’s time to take smoothies to a new level. 

In a world where health-conscious choices often take center stage, there’s an often overlooked corner of the nutrition space – smoothies that pack a caloric punch! 

As a Registered Dietitian, I understand the need for smoothies high in calories.

Contrary to the typical association of smoothies with low-calorie, diet-friendly options, we’re diving into a realm of rich, satisfying concoctions that not only tantalize your taste buds but also provide a hearty dose of energy -high calorie smoothies. 

We will list 9 simple recipes for smoothies high in calories, proving that sometimes, indulgence and wellness can go hand in hand. Get ready to blend, sip, and savor your way to a new appreciation for the high-calorie delight of smoothie perfection.

If you’re tired of bland and boring, and ready to elevate your smoothie game to new heights–keep reading!

Why Drink High Calorie Smoothies?

High calorie smoothies may not be for everybody. This is an ideal beverage for those struggling with weight gain or weight maintenance.

First, high calorie foods and drinks can help someone maintain weight or gain weight. While undergoing cancer treatment, the body requires extra nutrition to keep up with the demand. Therefore, increased calorie intake is essential. 

It is not ideal for patients to lose fat or muscle. Actually, it can be harmful to lose too much weight while undergoing treatment. 

So, high calorie shakes to help gain or maintain weight are a great place to start. 

Additionally, high calorie foods and beverages can help anyone having difficulty gaining or maintaining weight. This can be due to aging or other conditions. 

Second, smoothies are easy to tolerate for cancer patients or those with a decreased appetite. They can also be easy to prepare but some may need assistance. 

Smoothies can be sipped on at the patient’s leisure, are easy to drink, and are tolerable on the GI system. Typically your stomach won’t feel uncomfortably full but you’ll still obtain the necessary calories. Plus, they are perfect for patients that feel too tired to consume a full meal.

In other words, calorie dense smoothies can pack a lot of nutrition in a small portion size, making it easier to tolerate and obtain nutrients.

So, smoothies high in calories can provide extra nutrition in an easy to consume way! Weight gain smoothies are delicious and adjustable to meet your preferences and needs. 

The listed smoothies for weight gain work as a high calorie breakfast smoothie, snack, or dessert. 

If you’re interested in purchasing premade drinks, check out my article: Top 7 Nutritional Supplement Drinks for Cancer Patients.

Benefits of Smoothies High in Calories

As stated above, the #1 benefit is loaded nutrition in an easy to consume way. But, there are a lot of other benefits to smoothies high in calories.


Fruits and vegetables added to smoothies can add immune boosting antioxidants. Antioxidants reduce risk of many diseases.


Smoothies provide hydration given that they typically include water or ice. Fruit also provides hydration. Adequate fluid intake is often an overlooked part of a healthy diet.


The fruits and veggies added to shakes can provide gut happy fiber! Fiber promotes a healthy GI tract.


There are numerous smoothie additions to provide protein such as protein powder or Greek yogurt. Adequate protein intake can help prevent muscle loss.

Easy to Prepare

Typically, smoothies just require gathering and blending ingredients. High calorie shakes can be prepped and then blended prior to consumption.

Easy to Drink

High calorie drinks are an easy way to meet nutrition needs and for many, drinking is easier than chewing a full meal. This is especially true for patients undergoing treatments as they tend to feel fatigued.

Vitamins & Minerals

Smoothies can provide many vitamins and minerals based on the ingredients included. The options are limitless.

What you’ll Need for High Calorie Smoothies

There’s only a handful of things you’ll need to build a high calorie smoothie. 

  • Blender
  • Measuring Cups
  • Ingredients Listed


Of course, ingredients are essential for a high calorie smoothie. The options are endless. Below shows just a few recommendations when building your own smoothie.


  • Whole Milk
  • Half and Half
  • Heavy Cream
  • Soy Milk
  • Apple Juice
  • Orange Juice
  • Cranberry Juice
  • Pineapple Juice


Frozen fruit is a great option so you can omit the ice and still get a smoothie-like texture. Fruit adds a sweet flavor and is packed with nutrients.

  • Strawberries
  • Banana
  • Blueberries
  • Raspberries
  • Peaches
  • Pineapple
  • Avocado (yes- its a fruit!)


Veggies may be a little trickier to add to your smoothie and they tend to be more bitter. Below are options that blend well into a shake.

  • Spinach
  • Kale
  • Carrots
  • Zucchini
  • Squash
  • Frozen Riced Cauliflower


We can’t skip the protein in a high calorie smoothie. Protein is important to promote weight gain and maintenance. Plus, protein is important in muscle maintenance.

  • Greek Yogurt
  • Protein Powder
  • Nut Butter


Flavor is essential to tolerating a high calorie shake. Try these additions to meet your taste preferences.

  • Honey
  • Maple Syrup
  • Ice Cream
  • Sherbet
  • Coconut Cream
  • Coffee Creamer
  • Flavored Syrup (caramel, chocolate, strawberry)

High Calorie Smoothie Ingredient Swaps and Additions

So, some people utilize smoothies to lose weight. Proper smoothie ingredients are essential to make them high calorie and lead to weight gain or maintenance. 

Below are a few ingredient swaps to make your smoothie high calorie! 

  • Low Fat Yogurt -– Greek Yogurt or Cottage Cheese
  • Low Fat Milk — Whole Milk or Heavy Cream
  • Water — Milk or Juice
  • Ice — Frozen Fruit or Juice 


  • Tofu
  • Chia Seeds
  • Hemp Seeds
  • Flax Seeds
  • Cream Cheese
  • Peanut Butter
  • Almond Butter
  • Ice Cream
  • Avocado
  • Blended Oats
  • Coconut
  • Chocolate Syrup

Plant Based Alternatives: 

  • Plant Based Yogurt
  • Plant Based Milk (soy, coconut, oat)

Smoothie Adjustments

Your high calorie smoothie may not turn out perfect. Follow these tips for the texture you desire.

  • Too Thick: Add more Fluid (milk, juice, cream)
  • Too Thin/Watery: Add more Fruit, Veggies (fresh or frozen) 
  • For more Crystalized Texture: Add more Frozen Fruit
  • For Creamier Texture: Add Greek Yogurt
  • Sweetener: Maple Syrup, Honey, Sugar

Smoothies High in Calories

The goal of these smoothies are to provide a lot of nutrition in an easy to drink and easy to tolerate smoothie.

If sipping isn’t your thing, these can be consumed as smoothie bowls and eaten with a spoon. 

We list high calorie fruit smoothies plus dessert like smoothies for gaining weight. I suggest adjusting ingredients and measurements to meet your preferences. 

Let’s dive into some calorie rich shakes!

Quick Tip: Slice fruit (bananas, avocado) prior to freezing and freeze juice in an ice cube tray for easier preparation.

Chocolate Peanut Butter Cup


  • ½ Cup Greek Yogurt
  • 2 Tbsp Chocolate Protein Powder
  • 2-3 Tbsp Peanut Butter
  • 1 Tbsp Cocoa Powder or Chocolate Syrup (or both!) 
  • ½ Cup Heavy Cream
  • ½ Frozen Banana

Instructions: Measure all ingredients, add to blender and blend! 

Estimated Calories: 890 calories

Estimated Protein: 35 grams

Berries and Cream


  • ½ Cup Frozen Mixed Berries 
  • 3 Tbsp Softened Cream Cheese
  • 1 Tbsp Strawberry Jelly or Strawberry Syrup
  • 1 Tbsp Chia Seeds 
  • 1 Scoop Protein Powder
  • 1 Cup of Half and Half

Instructions: Measure all ingredients, add to blender and blend! 

Estimated Calories: 740 calories

Estimated Protein: 35g

Peanut Butter Banana Shake


  • 1 Frozen Banana
  • 3 Tbsp Peanut Butter
  • 1 Tbsp Full Fat Greek Yogurt
  • ½ Cup Ground Oats
  • 1 Cup Half and Half

Instructions: Measure all ingredients, blend oats. Add remaining ingredients to blender and blend! 

Estimated Calories:  865 calories

Estimated Protein: 24g

PB&J Smoothie


  • 6 Frozen Strawberries
  • 3 Tbsp Peanut Butter
  • 1 Tbsp Jelly or Jam
  • 1 Cup Heavy Cream

Instructions: Measure all ingredients, add to blender and blend! 

Estimated Calories: 1,186 calories

Estimated Protein: 18g

Carrot Cake Shake


  • 1 Cup Shredded Carrots
  • 1 Small Frozen Banana
  • 2 Tbsp Almond Butter
  • 2 Tbsp Cream Cheese
  • 1 Tbsp Plain Greek Yogurt
  • 1 Cup Pineapple Juice
  • ½ Cup Canned Coconut Milk
  • ½ tsp Cinnamon 
  • Pinch of Nutmeg and Ground Ginger

Instructions: Measure all ingredients, add to blender and blend! 

Estimated Calories: 800 calories

Estimated Protein: 15g

Chocolate Chunk Avocado


  • 1 Cup of Frozen Avocado 
  • 1 Scoop Chocolate Protein Powder
  • 1 Tbsp Chocolate Syrup
  • 1 Tbsp Hemp Seeds 
  • 1 Cup Half and Half

Instructions: Measure all ingredients, add to blender and blend! 

Estimated Calories: 745 calories

Estimated Protein: 45g

Strawberry Banana Smoothie

A classic strawberry banana smoothies with a high calorie twist.


  • 1 Frozen Banana (sliced)
  • 1 Cup Frozen Strawberries 
  • ¾ Cup Orange Juice
  • ½ Cup Full Fat Greek Yogurt
  • ⅓ Cup Whole Milk
  • 1 Scoop Vanilla Protein Powder

Instructions: Measure all ingredients, add to blender and blend! 

Estimated Calories: 705 calories

Estimated Protein: 25g

Chocolate Coconut

This one is like an Almond Joy!


  • 5oz Silken Tofu
  • 1 Scoop Chocolate Protein Powder
  • 2 Tbsp Shredded Coconut
  • ½ Cup Canned Coconut Milk
  • ½ Cup Whole Milk
  • 1 Tbsp Chocolate Syrup (more if desired)

Instructions: Measure all ingredients, add to blender and blend! 

Estimated Calories: 665 calories

Estimated Protein: 48g

Avocado Shake


  • 1 Cup Frozen Avocado
  • ½ Cup Frozen Pineapple
  • ½ Cup Pineapple Juice
  • ½ Cup Heavy Cream
  • ½ Cup Whole Milk Greek Yogurt
  • 1 Tbsp Flax Seeds

Instructions: Measure all ingredients, add to blender and blend! 

Estimated Calories: 1,1,45 calories

Estimated Protein: 19g

Calorie and protein estimates are estimates and will vary dependent on product. Most calorie and protein information was obtained through the USDA database.


I hope you enjoyed your weight gain smoothie! 

Be sure to head back to the Blog Page to check out more high calorie foods!

Other Posts you may Enjoy

Leave a Comment

Your email address will not be published. Required fields are marked *

Scroll to Top